Gene Signatures of NEUROGENIN3+ Endocrine Progenitor Cells in the Human Pancreas

Gene Signatures of NEUROGENIN3+ Endocrine Progenitor Cells in the Human Pancreas

NEUROGENIN3+ (NEUROG3+) cells are considered to be pancreatic endocrine progenitors. Our current knowledge on the molecular program of NEUROG3+ cells in humans is largely extrapolated from studies in mice. We hypothesized that single-cell RNA-seq enables in-depth exploration of the rare NEUROG3+ cel...

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Bibliographic Details
Main Authors: Hyo Jeong Yong, Gengqiang Xie, Chengyang Liu, Wei Wang, Ali Naji, Jerome Irianto, Yue J. Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Endocrinology
Subjects:
NEUROG3
endocrine progenitor
epsilon cells
human pancreas
single-cell RNA-seq
data integration
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.736286/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2021.736286/full

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