Immune Suppression in Tumors as a Surmountable Obstacle to Clinical Efficacy of Cancer Vaccines

Human tumors are usually not spontaneously eliminated by the immune system and therapeutic vaccination of cancer patients with defined antigens is followed by tumor regressions only in a small minority of the patients. The poor vaccination effectiveness could be explained by an immunosuppressive tum...

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Bibliographic Details
Main Authors: Danièle Godelaine, Pierre Van der Bruggen, Grégoire Wieërs, Nathalie Demotte
Format: Article
Language:English
Published: MDPI AG 2011-07-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/3/3/2904/