Single-Cell RNA-Seq Analysis Uncovers Distinct Functional Human NKT Cell Sub-Populations in Peripheral Blood

Single-Cell RNA-Seq Analysis Uncovers Distinct Functional Human NKT Cell Sub-Populations in Peripheral Blood

Vα24-invariant human natural killer T (NKT) cells comprise a unique subset of CD1d-restricted T cells with potent immune regulatory function and are involved in the development of a variety of human diseases. However, the lack of comprehensive molecular subset identities limits their objective class...

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Bibliographic Details
Main Authors: Li Zhou, Indra Adrianto, Jie Wang, Xiaojun Wu, Indrani Datta, Qing-Sheng Mi
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
natural killer T cells
single cell RNA sequencing
peripheral blood mononucleotide cells
gene express profile
cell population analysis
cell survival and proliferation
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00384/full

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