Pure Erythroid Leukemia in a Sickle Cell Patient Treated with Hydroxyurea

We present a very rare case of pure erythroid leukemia arising in a young patient with sickle cell disease being treated with hydroxyurea for almost 5 years. Diagnosing and managing this rare condition has been a challenge and the majority of patients with pure erythroid leukemia have a very poor pr...

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Main Authors: Dhiraj Kumar Yadav, Thushara Paul, Mohamed Alhamar, Kedar Inamdar, Yue Guo
Format: Article
Language:English
Published: Karger Publishers 2020-07-01
Series:Case Reports in Oncology
Subjects:
Online Access:https://www.karger.com/Article/FullText/508361
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spelling doaj-ec358672470b45eca317954ad8804ba02020-11-25T03:52:02ZengKarger PublishersCase Reports in Oncology1662-65752020-07-0113285786210.1159/000508361508361Pure Erythroid Leukemia in a Sickle Cell Patient Treated with HydroxyureaDhiraj Kumar YadavThushara PaulMohamed AlhamarKedar InamdarYue GuoWe present a very rare case of pure erythroid leukemia arising in a young patient with sickle cell disease being treated with hydroxyurea for almost 5 years. Diagnosing and managing this rare condition has been a challenge and the majority of patients with pure erythroid leukemia have a very poor prognosis with survival in months despite treatment. This form of leukemia could be therapy related and in our case, hydroxyurea may have been responsible for the development of this aggressive condition.https://www.karger.com/Article/FullText/508361pure erythroid leukemiasickle cell anemiahydroxyureatoxicity
collection DOAJ
language English
format Article
sources DOAJ
author Dhiraj Kumar Yadav
Thushara Paul
Mohamed Alhamar
Kedar Inamdar
Yue Guo
spellingShingle Dhiraj Kumar Yadav
Thushara Paul
Mohamed Alhamar
Kedar Inamdar
Yue Guo
Pure Erythroid Leukemia in a Sickle Cell Patient Treated with Hydroxyurea
Case Reports in Oncology
pure erythroid leukemia
sickle cell anemia
hydroxyurea
toxicity
author_facet Dhiraj Kumar Yadav
Thushara Paul
Mohamed Alhamar
Kedar Inamdar
Yue Guo
author_sort Dhiraj Kumar Yadav
title Pure Erythroid Leukemia in a Sickle Cell Patient Treated with Hydroxyurea
title_short Pure Erythroid Leukemia in a Sickle Cell Patient Treated with Hydroxyurea
title_full Pure Erythroid Leukemia in a Sickle Cell Patient Treated with Hydroxyurea
title_fullStr Pure Erythroid Leukemia in a Sickle Cell Patient Treated with Hydroxyurea
title_full_unstemmed Pure Erythroid Leukemia in a Sickle Cell Patient Treated with Hydroxyurea
title_sort pure erythroid leukemia in a sickle cell patient treated with hydroxyurea
publisher Karger Publishers
series Case Reports in Oncology
issn 1662-6575
publishDate 2020-07-01
description We present a very rare case of pure erythroid leukemia arising in a young patient with sickle cell disease being treated with hydroxyurea for almost 5 years. Diagnosing and managing this rare condition has been a challenge and the majority of patients with pure erythroid leukemia have a very poor prognosis with survival in months despite treatment. This form of leukemia could be therapy related and in our case, hydroxyurea may have been responsible for the development of this aggressive condition.
topic pure erythroid leukemia
sickle cell anemia
hydroxyurea
toxicity
url https://www.karger.com/Article/FullText/508361
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