Does fesoterodine have a role in the treatment of poorly managed patients with overactive bladder?

• Main Authors: Morris V, Wagg A
• Format: Article
• Language: English
• Published: Dove Medical Press 2014-01-01
• Series: Drug Design, Development and Therapy
• Online Access: http://www.dovepress.com/does-fesoterodine-have-a-role-in-the-treatment-of-poorly-managed-patie-peer-reviewed-article-DDDT

Vikky Morris,1 Adrian Wagg21Geriatric Medicine, Taunton Hospital Somerset, UK; 2Division of Geriatric Medicine, University of Alberta, Edmonton, Alberta, CanadaAbstract: Overactive bladder (OAB), a clinically defined symptom complex comprising urinary urgency, usually accompanied by urinary frequency and nocturia, with or without urgency incontinence, is common and has a markedly negative impact on the sufferer's quality of life. Following conservative and lifestyle management, the current pharmacological mainstay of treatment is antimuscarinic therapy. This review explores the role of fesoterodine, a relatively recently introduced antimuscarinic agent, in the treatment of patients who may have had a suboptimal response to initial therapy, who have switched treatment from tolterodine, or may be at risk of receiving poor treatment because of either multimorbidity or complex polypharmacy.Keywords: elderly, fesoterodine, overactive bladder, urgency incontinence