Use of the FINDRISC Questionnaire in the Uzbek Population as a First Stage of Screening for Type 2 Diabetes Mellitus

• Main Authors: Anna V. Alieva, Saydiganikhodja I. Ismailov, Gulnara N. Rakhimova
• Format: Article
• Language: English
• Published: International Medical Research and Development Corporation 2020-03-01
• Series: International Journal of Biomedicine
• Subjects: type 2 diabetes; screening; ethnicity; risk assessment
• Online Access: http://ijbm.org/articles/i37/ijbm_10(1)_oa3.pdf
• ISSN: 2158-0510; 2158-0529

Background: Active diagnosis of rapidly growing type 2 diabetes (T2D) is very important. Whether the FINDRISC questionnaire can be used as a first-stage screening tool in the Uzbek population is unclear, as anthropometric parameters and the impact of each risk factor may differ in different populations. Materials and Results: In 2015–2016, regardless of nationality 2521 people (711 men and 1464 women) living in urban and rural areas of Uzbekistan were examined. The study included filling out a FINDRISC questionnaire with an assessment of the risk for T2D. All subjects underwent OGTT and HbA1c testing. The average score on the FINDRISC questionnaire among people with newly diagnosed diabetes was 12.8±0.4 (P<0.001), for IGT – 11.4±0.4 (P<0.001), for IFG – 11.0±0.8 (P<0.001) compared with individuals without carbohydrate metabolism disorders (8.0±0.09). Among people with diabetes diagnosed during the screening, only 33.9% had a high (30%) and very high (3.9%) risk of T2D, while 27.6% had a moderate risk, 30% - an increased risk, and 8.7% - a low risk of T2D. For the FINDRISC score, the sensitivity with a threshold value of 9 points was 87.9% and specificity was 45.3%; with a value of 12 points, sensitivity was 71.6% and specificity was 54.8%. Conclusion: These results were the basis for a multivariate analysis of the risk for T2D among people of Uzbek nationality, and for the development of our own risk assessment program.