E-cadherin genetic variants predict survival outcome in breast cancer patients

E-cadherin genetic variants predict survival outcome in breast cancer patients

Abstract Background E-cadherin is a major component of adherens junctions that regulates cell shape and maintains tissue integrity. A complete loss or any decrease in cell surface expression of E-cadherin will interfere with the cell-to-cell junctions’ strength and leads to cell detachment and escap...

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Bibliographic Details
Main Authors: Hager Memni, Yosra Macherki, Zahra Klayech, Ahlem Ben-Haj-Ayed, Karim Farhat, Yassmine Remadi, Sallouha Gabbouj, Wijden Mahfoudh, Nadia Bouzid, Noureddine Bouaouina, Lotfi Chouchane, Abdelfattah Zakhama, Elham Hassen
Format: Article
Language:English
Published: BMC 2016-11-01
Series:Journal of Translational Medicine
Subjects:
E-cadherin
SNP
Prognosis
Breast cancer
Online Access:http://link.springer.com/article/10.1186/s12967-016-1077-4

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