Activin A Modulates CRIPTO-1/HNF4α+ Cells to Guide Cardiac Differentiation from Human Embryonic Stem Cells

Activin A Modulates CRIPTO-1/HNF4α+ Cells to Guide Cardiac Differentiation from Human Embryonic Stem Cells

The use of human pluripotent stem cells in basic and translational cardiac research requires efficient differentiation protocols towards cardiomyocytes. In vitro differentiation yields heterogeneous populations of ventricular-, atrial-, and nodal-like cells hindering their potential applications in...

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Bibliographic Details
Main Authors: Robin Duelen, Guillaume Gilbert, Abdulsamie Patel, Nathalie de Schaetzen, Liesbeth De Waele, Llewelyn Roderick, Karin R. Sipido, Catherine M. Verfaillie, Gunnar M. Buyse, Lieven Thorrez, Maurilio Sampaolesi
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2017/4651238

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