Refolding Process of Cysteine-Rich Proteins: Chitinase as a Model
Background: Recombinant proteins overexpressed in E. coli are usually deposited in inclusion bodies. Cysteines in the protein contribute to this process. Inter- and intra- molecular disulfide bonds in chitinase, a cysteine-rich protein, cause aggregation when the recombinant protein is overexpressed...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Varastegan Institute for Medical Sciences
2015-10-01
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| Series: | Reports of Biochemistry and Molecular Biology |
| Subjects: | |
| Online Access: | http://rbmb.net/article-1-67-en.pdf |