In Vitro Evaluation of the Combination of <i>Melaleuca alternifolia</i> (Tea Tree) Oil and Dimethyl Sulfoxide (DMSO) against Trophozoites and Cysts of <i>Acanthamoeba</i> Strains. Oxygen Consumption Rate (OCR) Assay as a Method for Drug Screening

In Vitro Evaluation of the Combination of <i>Melaleuca alternifolia</i> (Tea Tree) Oil and Dimethyl Sulfoxide (DMSO) against Trophozoites and Cysts of <i>Acanthamoeba</i> Strains. Oxygen Consumption Rate (OCR) Assay as a Method for Drug Screening

Ameobae belonging to the genus <i>Acanthamoeba</i> are responsible for the human diseases Acanthamoeba keratitis (AK) and granulomatous amoebic encephalitis (GAE). The treatment of these illnesses is hampered by the existence of a resistance stage (cysts). In an attempt to add new agents...

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Bibliographic Details
Main Authors: Tania Martín-Pérez, Irene Heredero-Bermejo, Cristina Verdú-Expósito, Jorge Pérez-Serrano
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Pathogens
Subjects:
<i>Acanthamoeba</i> spp.
genotype T3
genotype T4
cysts
dimethyl sulfoxide
tea tree oil
Online Access:https://www.mdpi.com/2076-0817/10/4/491

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