Extensive skin necrosis after periprosthetic knee infection: a case that highlights the possibility of complications induced by low-molecular-weight heparin

<p>We describe a case of a patient with atrial fibrillation, anticoagulated with dabigatran, that developed severe knee skin necrosis in the setting of an acute periprosthetic knee infection, after initiating low-molecular-weight heparin. A wide range of etiology hypotheses was discussed withi...

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Main Authors: H. Fonte, A. Carvalho, J. Rosa, C. Pereira, A. Pereira, R. Sousa
Format: Article
Language:English
Published: Copernicus Publications 2021-06-01
Series:Journal of Bone and Joint Infection
Online Access:https://jbji.copernicus.org/articles/6/235/2021/jbji-6-235-2021.pdf
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spelling doaj-ebfddb3b3df74b58a9dc7d0dc67466ec2021-06-28T11:35:31ZengCopernicus PublicationsJournal of Bone and Joint Infection2206-35522021-06-01623524010.5194/jbji-6-235-2021Extensive skin necrosis after periprosthetic knee infection: a case that highlights the possibility of complications induced by low-molecular-weight heparinH. Fonte0A. Carvalho1J. Rosa2C. Pereira3C. Pereira4A. Pereira5R. Sousa6R. Sousa7Department of Orthopaedics, Centro Hospitalar Universitário do Porto, Porto, PortugalDepartment of Orthopaedics, Centro Hospitalar Universitário do Porto, Porto, PortugalDepartment of Orthopaedics, Centro Hospitalar Universitário do Porto, Porto, PortugalDepartment of Internal Medicine, Centro Hospitalar Universitário do Porto, Porto, PortugalGRIP (Porto Bone and Joint Infection Unit), Centro Hospitalar Universitário do Porto, Porto, PortugalDepartment of Orthopaedics, Centro Hospitalar Universitário do Porto, Porto, PortugalDepartment of Orthopaedics, Centro Hospitalar Universitário do Porto, Porto, PortugalGRIP (Porto Bone and Joint Infection Unit), Centro Hospitalar Universitário do Porto, Porto, Portugal<p>We describe a case of a patient with atrial fibrillation, anticoagulated with dabigatran, that developed severe knee skin necrosis in the setting of an acute periprosthetic knee infection, after initiating low-molecular-weight heparin. A wide range of etiology hypotheses was discussed within a multidisciplinary team. The complex approach consisted of treating the underlying infection, multiple types of soft-tissue management, and stopping enoxaparin.</p>https://jbji.copernicus.org/articles/6/235/2021/jbji-6-235-2021.pdf
collection DOAJ
language English
format Article
sources DOAJ
author H. Fonte
A. Carvalho
J. Rosa
C. Pereira
C. Pereira
A. Pereira
R. Sousa
R. Sousa
spellingShingle H. Fonte
A. Carvalho
J. Rosa
C. Pereira
C. Pereira
A. Pereira
R. Sousa
R. Sousa
Extensive skin necrosis after periprosthetic knee infection: a case that highlights the possibility of complications induced by low-molecular-weight heparin
Journal of Bone and Joint Infection
author_facet H. Fonte
A. Carvalho
J. Rosa
C. Pereira
C. Pereira
A. Pereira
R. Sousa
R. Sousa
author_sort H. Fonte
title Extensive skin necrosis after periprosthetic knee infection: a case that highlights the possibility of complications induced by low-molecular-weight heparin
title_short Extensive skin necrosis after periprosthetic knee infection: a case that highlights the possibility of complications induced by low-molecular-weight heparin
title_full Extensive skin necrosis after periprosthetic knee infection: a case that highlights the possibility of complications induced by low-molecular-weight heparin
title_fullStr Extensive skin necrosis after periprosthetic knee infection: a case that highlights the possibility of complications induced by low-molecular-weight heparin
title_full_unstemmed Extensive skin necrosis after periprosthetic knee infection: a case that highlights the possibility of complications induced by low-molecular-weight heparin
title_sort extensive skin necrosis after periprosthetic knee infection: a case that highlights the possibility of complications induced by low-molecular-weight heparin
publisher Copernicus Publications
series Journal of Bone and Joint Infection
issn 2206-3552
publishDate 2021-06-01
description <p>We describe a case of a patient with atrial fibrillation, anticoagulated with dabigatran, that developed severe knee skin necrosis in the setting of an acute periprosthetic knee infection, after initiating low-molecular-weight heparin. A wide range of etiology hypotheses was discussed within a multidisciplinary team. The complex approach consisted of treating the underlying infection, multiple types of soft-tissue management, and stopping enoxaparin.</p>
url https://jbji.copernicus.org/articles/6/235/2021/jbji-6-235-2021.pdf
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