Wnt16 Signaling Is Required for IL-1β-Induced Matrix Metalloproteinase-13-Regulated Proliferation of Human Stem Cell-Derived Osteoblastic Cells

Wnt16 Signaling Is Required for IL-1β-Induced Matrix Metalloproteinase-13-Regulated Proliferation of Human Stem Cell-Derived Osteoblastic Cells

We established a differentiation method for homogeneous α7 integrin-positive human skeletal muscle stem cell (α7+hSMSC)-derived osteoblast-like (α7+hSMSC-OB) cells, and found that interleukin (IL)-1β induces matrix metalloproteinase (MMP)-13-regulated proliferation of these cells. These data suggest...

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Bibliographic Details
Main Authors: Nobuaki Ozeki, Makio Mogi, Naoko Hase, Taiki Hiyama, Hideyuki Yamaguchi, Rie Kawai, Ayami Kondo, Kazuhiko Nakata
Format: Article
Language:English
Published: MDPI AG 2016-02-01
Series:International Journal of Molecular Sciences
Subjects:
Wnt16
matrix metalloproteinase
osteoblast
interleukin-1β
cell proliferation
Online Access:http://www.mdpi.com/1422-0067/17/2/221

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