Targeting of IL-10R on acute myeloid leukemia blasts with chimeric antigen receptor-expressing T cells
Abstract Acute myeloid leukemia (AML) is a biologically and clinically heterogeneous disease with a dismal prognosis and limited treatment options. Chimeric antigen receptor (CAR) T cells have achieved unprecedented clinical responses in patients with B cell malignancies but a dismal consequences in...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-08-01
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Series: | Blood Cancer Journal |
Online Access: | https://doi.org/10.1038/s41408-021-00536-x |