Rapid and robust antibody Fab fragment crystallization utilizing edge-to-edge beta-sheet packing.
Antibody therapeutics are one of the most important classes of drugs. Antibody structures have become an integral part of predicting the behavior of potential therapeutics, either directly or as the basis of modeling. Structures of Fab:antigen complexes have even greater value. While the crystalliza...
Main Authors: | Ricky Lieu, Stephen Antonysamy, Zhanna Druzina, Carolyn Ho, N Rebecca Kang, Anna Pustilnik, Jing Wang, Shane Atwell |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2020-01-01
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Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0232311 |
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