Collapsing Focal Segmental Glomerulosclerosis in a Patient with Systemic Lupus Erythematosus

Collapsing Focal Segmental Glomerulosclerosis in a Patient with Systemic Lupus Erythematosus

We present a case of a 36-year-old female from Ghana who presented with atypical chest pain and shortness of breath and was found to have bilateral transudative pleural effusion and trivial pericardial effusion. Further work-up revealed serological markers consistent with active lupus and negative H...

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Main Authors: Hassan Tariq, Arsalan Rafiq, Giovanni Franchin
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2014/732192
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spelling doaj-ebd9a191e0b74ba790b657b23949b9672020-11-25T01:09:01ZengHindawi LimitedCase Reports in Medicine1687-96271687-96352014-01-01201410.1155/2014/732192732192Collapsing Focal Segmental Glomerulosclerosis in a Patient with Systemic Lupus ErythematosusHassan Tariq0Arsalan Rafiq1Giovanni Franchin2Bronx Lebanon Hospital Center, Department of Medicine, 1650 Selwyn Avenue, Suit 10C, Bronx, NY 10457, USABronx Lebanon Hospital Center, Department of Medicine, 1650 Selwyn Avenue, Suit 10C, Bronx, NY 10457, USABronx Lebanon Hospital Center, Department of Medicine, 1650 Selwyn Avenue, Suit 10C, Bronx, NY 10457, USAWe present a case of a 36-year-old female from Ghana who presented with atypical chest pain and shortness of breath and was found to have bilateral transudative pleural effusion and trivial pericardial effusion. Further work-up revealed serological markers consistent with active lupus and negative HIV. She developed rapid deterioration of her renal function requiring dialysis. Her renal biopsy showed collapsing focal segmental glomerulosclerosis with diffuse mesangial proliferative glomerulonephritis, consistent with lupus nephritis class II along with tubular degenerative changes. She was started on high dose steroids and later on mycophenolate mofetil. Her renal function slowly recovered to baseline.http://dx.doi.org/10.1155/2014/732192
collection DOAJ
language English
format Article
sources DOAJ
author Hassan Tariq
Arsalan Rafiq
Giovanni Franchin
spellingShingle Hassan Tariq
Arsalan Rafiq
Giovanni Franchin
Collapsing Focal Segmental Glomerulosclerosis in a Patient with Systemic Lupus Erythematosus
Case Reports in Medicine
author_facet Hassan Tariq
Arsalan Rafiq
Giovanni Franchin
author_sort Hassan Tariq
title Collapsing Focal Segmental Glomerulosclerosis in a Patient with Systemic Lupus Erythematosus
title_short Collapsing Focal Segmental Glomerulosclerosis in a Patient with Systemic Lupus Erythematosus
title_full Collapsing Focal Segmental Glomerulosclerosis in a Patient with Systemic Lupus Erythematosus
title_fullStr Collapsing Focal Segmental Glomerulosclerosis in a Patient with Systemic Lupus Erythematosus
title_full_unstemmed Collapsing Focal Segmental Glomerulosclerosis in a Patient with Systemic Lupus Erythematosus
title_sort collapsing focal segmental glomerulosclerosis in a patient with systemic lupus erythematosus
publisher Hindawi Limited
series Case Reports in Medicine
issn 1687-9627
1687-9635
publishDate 2014-01-01
description We present a case of a 36-year-old female from Ghana who presented with atypical chest pain and shortness of breath and was found to have bilateral transudative pleural effusion and trivial pericardial effusion. Further work-up revealed serological markers consistent with active lupus and negative HIV. She developed rapid deterioration of her renal function requiring dialysis. Her renal biopsy showed collapsing focal segmental glomerulosclerosis with diffuse mesangial proliferative glomerulonephritis, consistent with lupus nephritis class II along with tubular degenerative changes. She was started on high dose steroids and later on mycophenolate mofetil. Her renal function slowly recovered to baseline.
url http://dx.doi.org/10.1155/2014/732192
work_keys_str_mv AT hassantariq collapsingfocalsegmentalglomerulosclerosisinapatientwithsystemiclupuserythematosus
AT arsalanrafiq collapsingfocalsegmentalglomerulosclerosisinapatientwithsystemiclupuserythematosus
AT giovannifranchin collapsingfocalsegmentalglomerulosclerosisinapatientwithsystemiclupuserythematosus
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