Intramolecular Barbier reaction in water: cyclopentane and cyclohexane ring closure

• Main Authors: RADOMIR N. SAICIC, RADOMIR MATOVIC, ALEKSANDAR IVKOVIC
• Format: Article
• Language: English
• Published: Serbian Chemical Society 2002-03-01
• Series: Journal of the Serbian Chemical Society
• Subjects: Barbier reactions; cyclisation; allylation; allenes; zinc; indium
• Online Access: http://www.shd.org.yu/HtDocs/SHD/Vol67/No3/V67-No3-01.pdf
• ISSN: 0352-5139

Zinc or indium promoted intramolecular Barbier reactions of aldehydes containing a suitably positioned allylic or propargylic halide unit afford unsaturated cyclic alcohols in moderate yields.