UPF2 is a critical regulator of liver development, function and regeneration.

<h4>Background</h4>Nonsense-mediated mRNA decay (NMD) is a post-transcriptional RNA surveillance process that facilitates the recognition and destruction of mRNAs bearing premature terminations codons (PTCs). Such PTC-containing (PTC+) mRNAs may arise from different processes, including...

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Main Authors: Lina A Thoren, Gitte A Nørgaard, Joachim Weischenfeldt, Johannes Waage, Janus S Jakobsen, Inge Damgaard, Frida C Bergström, Anna M Blom, Rehannah Borup, Hanne Cathrine Bisgaard, Bo T Porse
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-07-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20657840/?tool=EBI