Preoperative stereotactic radiosurgery for brain metastases: the STEP study protocol for a multicentre, prospective, phase-II trial

Preoperative stereotactic radiosurgery for brain metastases: the STEP study protocol for a multicentre, prospective, phase-II trial

Abstract Background Surgery is an important therapeutic option for brain metastases. Currently, postoperative stereotactic radiosurgery (SRT) leads to 6-month and 1-year local control estimated at 70 and 62% respectively. However, there is an increased risk of radio-necrosis and leptomeningeal relap...

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Bibliographic Details
Main Authors: Angeline Ginzac, Guillaume Dupic, Lucie Brun, Ioana Molnar, Mélanie Casile, Xavier Durando, Pierre Verrelle, Jean-Jacques Lemaire, Toufic Khalil, Julian Biau
Format: Article
Language:English
Published: BMC 2021-07-01
Series:BMC Cancer
Subjects:
Brain metastases
Preoperative stereotactic radiotherapy
Local control
Radio-necrosis
Overall survival
Online Access:https://doi.org/10.1186/s12885-021-08602-0

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