Hepatoprotective Effects of Fumaria parviflora L. on CCl4–induced hepatotoxicity
Background: Liver, the largest internal organ in the body, plays a central role in many essential physiologic processes and has numerous functions. Nevertheless, its disorders are many fold. Hepatic disease may result from a variety of therapeutic drugs or toxins that cause wide hepatic lesions. Obj...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Institue of Medicinal Plants, ACECR
2006-09-01
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| Series: | Journal of Medicinal Plants |
| Subjects: | |
| Online Access: | http://jmp.ir/article-1-662-en.html |
| Summary: | Background: Liver, the largest internal organ in the body, plays a central role in many essential physiologic processes and has numerous functions. Nevertheless, its disorders are many fold. Hepatic disease may result from a variety of therapeutic drugs or toxins that cause wide hepatic lesions. Objective: From the old times, plants have been used for the treatment of liver disorders. In this study, protective effect of hydroalcoholic extract of Fumaria parviflora L was determined. Methods: Male rats were used in this study. In the test groups, they received l00, 200 and 300mg/kg of the extract, alone or with CCl4 (3ml/kg). The liver function test and hystopathological observations were performed for all groups. Results: Carbon tetrachloride caused sever liver damage and the extract of the plant with doses higher than l00mg/kg prevented CCl4-induced liver damage Conclusion: The results of the present study support the traditional beliefs on hepatoprotective effects of Fumaria parviflora |
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| ISSN: | 2717-204X 2717-2058 |