CHRNA7 polymorphisms and response to cholinesterase inhibitors in Alzheimer's disease.

CHRNA7 polymorphisms and response to cholinesterase inhibitors in Alzheimer's disease.

BACKGROUND: CHRNA7 encodes the α7 nicotinic acetylcholine receptor subunit, which is important to Alzheimer's disease (AD) pathogenesis and cholinergic neurotransmission. Previously, CHRNA7 polymorphisms have not been related to cholinesterase inhibitors (ChEI) response. METHODS: Mild to modera...

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Bibliographic Details
Main Authors:	Pei-Hsuan Weng, Jen-Hau Chen, Ta-Fu Chen, Yu Sun, Li-Li Wen, Ping-Keung Yip, Yi-Min Chu, Yen-Ching Chen
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2013-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC3877150?pdf=render

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