NRF2 is required for structural and metabolic maturation of human induced pluripotent stem cell-derived ardiomyocytes

NRF2 is required for structural and metabolic maturation of human induced pluripotent stem cell-derived ardiomyocytes

Abstract Background Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) hold great promise for regenerative medicine and in drugs screening. Despite displaying key cardiomyocyte phenotypic characteristics, they more closely resemble fetal/neonatal cardiomyocytes and are still imma...

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Bibliographic Details
Main Authors:	Xinyuan Zhang, Liang Ye, Hao Xu, Qin Zhou, Bin Tan, Qin Yi, Liang Yan, Min Xie, Yin Zhang, Jie Tian, Jing Zhu
Format:	Article
Language:	English
Published:	BMC 2021-03-01
Series:	Stem Cell Research & Therapy
Subjects:	Nuclear factor erythroid 2 p45-related factor 2 (NRF2) Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) Metabolism
Online Access:	https://doi.org/10.1186/s13287-021-02264-2

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