TULA-2 Deficiency Enhances Platelet Functional Responses to CLEC-2 Agonists

TULA-2 Deficiency Enhances Platelet Functional Responses to CLEC-2 Agonists

Platelet activation is essential for hemostasis. Central to platelet activation are the signals transmitted through surface receptors such as glycoprotein VI, the protease-activated receptors, and C-type lectin-like receptor 2 (CLEC-2). CLEC-2 is a HemITAM (hem-immunoreceptor tyrosine activation mot...

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Bibliographic Details
Main Authors: John C. Kostyak, Benjamin R. Mauri, Carol Dangelmaier, Akruti Patel, Yuhang Zhou, Johannes A. Eble, Alexander Y. Tsygankov, Steven E. McKenzie, Satya P. Kunapuli
Format: Article
Language:English
Published: Georg Thieme Verlag KG 2018-10-01
Series:TH Open
Subjects:
platelets
thrombosis
thromboxane a2
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1676358

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