The EyeFlowCell: Development of a 3D-Printed Dissolution Test Setup for Intravitreal Dosage Forms

The EyeFlowCell: Development of a 3D-Printed Dissolution Test Setup for Intravitreal Dosage Forms

An in vitro dissolution model, the so-called EyeFlowCell (EFC), was developed to test intravitreal dosage forms, simulating parameters such as the gel-like consistency of the vitreous body. The developed model consists of a stereolithography 3D-printed flow-through cell with a polyacrylamide (PAA) g...

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Bibliographic Details
Main Authors: Tobias Auel, Linus Großmann, Lukas Schulig, Werner Weitschies, Anne Seidlitz
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Pharmaceutics
Subjects:
in vitro model
in vitro drug release
intravitreal implants
SLA 3D-printing
triamcinolone acetonide
USP apparatus 4
Online Access:https://www.mdpi.com/1999-4923/13/9/1394

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