Evaluation of acetone as a solvent for the Ames test

Abstract Background Acetone is a common alternative solvent used in the Ames test when test chemicals are unstable or poorly soluble in water or dimethyl sulfoxide (DMSO). Yet, there is a very limited number of studies evaluating acetone as a solvent in the modified Ames test with preincubation (pre...

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Bibliographic Details
Main Authors: Tomomi Shibata, Takeshi Yamagata, Akihiro Kawade, Shoji Asakura, Naoki Toritsuka, Naoki Koyama, Atsushi Hakura
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Genes and Environment
Subjects:
Online Access:https://doi.org/10.1186/s41021-020-0143-6