Exosomes derived from umbilical cord mesenchymal stem cells reduce microglia-mediated neuroinflammation in perinatal brain injury

Exosomes derived from umbilical cord mesenchymal stem cells reduce microglia-mediated neuroinflammation in perinatal brain injury

Abstract Background Preterm newborns are at high risk of developing neurodevelopmental deficits caused by neuroinflammation leading to perinatal brain injury. Human Wharton’s jelly mesenchymal stem cells (hWJ-MSC) derived from the umbilical cord have been suggested to reduce neuroinflammation, in pa...

Full description

Bibliographic Details
Main Authors: Gierin Thomi, Daniel Surbek, Valérie Haesler, Marianne Joerger-Messerli, Andreina Schoeberlein
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Stem Cell Research & Therapy
Subjects:
Preterm birth
Perinatal brain damage
White matter injury
Neuroinflammation
Hypoxia-ischemia
Mesenchymal stem cells
Online Access:http://link.springer.com/article/10.1186/s13287-019-1207-z

Internet

http://link.springer.com/article/10.1186/s13287-019-1207-z

Similar Items