Interleukin-10 (IL-10) pathway: genetic variants and outcomes of HIV-1 infection in African American adolescents.

Immunological and clinical outcomes can vary considerably at the individual and population levels during both treated and untreated HIV-1 infection. Cytokines encoded by the interleukin-10 gene (IL10) family have broad immunomodulatory function in viral persistence, and several SNPs in the IL10 prom...

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Bibliographic Details
Main Authors: Sadeep Shrestha, Howard W Wiener, Brahim Aissani, Wei Song, Aditi Shendre, Craig M Wilson, Richard A Kaslow, Jianming Tang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2954785?pdf=render