The guanine-nucleotide exchange factor SGEF plays a crucial role in the formation of atherosclerosis.

The guanine-nucleotide exchange factor SGEF plays a crucial role in the formation of atherosclerosis.

The passage of leukocytes across the endothelium and into arterial walls is a critical step in the development of atherosclerosis. Previously, we showed in vitro that the RhoG guanine nucleotide exchange factor SGEF (Arhgef26) contributes to the formation of ICAM-1-induced endothelial docking struct...

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Bibliographic Details
Main Authors: Thomas Samson, Jaap D van Buul, Jeffrey Kroon, Christopher Welch, Erik N Bakker, Hanke L Matlung, Timo K van den Berg, Lisa Sharek, Claire Doerschuk, Klaus Hahn, Keith Burridge
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3555862?pdf=render

Internet

http://europepmc.org/articles/PMC3555862?pdf=render

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