Co-Transplantation of Plasmid-Transfected Myoblasts and Myotubes into Rat Brains Enables High Levels of Gene Expression Long-Term
We have previously proposed the use of primary muscle cells as a “platform,” or “vehicle” for intracerebral transgene expression. Brain grafts of minced muscle, or cultured muscle cells persisted in rat brains for at least 6 mo without any decrease in graft size, or tumor formation. Stable, but mode...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
1993-05-01
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Series: | Cell Transplantation |
Online Access: | https://doi.org/10.1177/096368979300200302 |