Graves' disease is associated with a defective expression of the immune regulatory molecule galectin-9 in antigen-presenting dendritic cells.

Patients with autoimmune thyroid disease (AITD) show defects in their immune-regulatory mechanisms. Herein we assessed the expression and function of galectin-1 and galectin-9 (Gal-1, Gal-9) in dendritic cells (DCs) from patients with AITD.Peripheral blood samples from 25 patients with Graves'...

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Main Authors: Susanna Leskela, Ana Serrano, Hortensia de la Fuente, Ana Rodríguez-Muñoz, Ana Ramos-Levi, Miguel Sampedro-Nuñez, Francisco Sánchez-Madrid, Roberto González-Amaro, Mónica Marazuela
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4399981?pdf=render