Mode of induction of platelet-derived extracellular vesicles is a critical determinant of their phenotype and function

Abstract Platelet-derived extracellular vesicles (PDEVs) are the most abundant amongst all types of EVs in the circulation. However, the mechanisms leading to PDEVs release, their role in coagulation and phenotypic composition are poorly understood. PDEVs from washed platelets were generated using d...

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Bibliographic Details
Main Authors: P. M. Ferreira, E. Bozbas, S. D. Tannetta, N. Alroqaiba, R. Zhou, J. T. B. Crawley, J. M. Gibbins, C. I. Jones, J. Ahnström, P. Yaqoob
Format: Article
Language:English
Published: Nature Publishing Group 2020-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-73005-3