2-(3,4-Dimethoxyphenyl)-<i>N</i>-(4-methoxyphenyl)-1-propyl-1<i>H</i>-benzo[<i>d</i>]imidazole-5-carboxamide

• Main Authors: Prakash Bhaskar, Vasantha Kumar, Suresha Kumara Tholappanavara Hanumanthappa, Sowmya Haliwana Banakara Vijaykumar
• Format: Article
• Language: English
• Published: MDPI AG 2019-09-01
• Series: Molbank
• Subjects: benzimidazole; carboxamide; one-pot synthesis; reductive cyclization
• Online Access: https://www.mdpi.com/1422-8599/2019/3/M1079
• ISSN: 1422-8599

2-(3,4-Dimethoxyphenyl)-<i>N</i>-(4-methoxyphenyl)-1-propyl-1<i>H</i>-benzo[<i>d</i>]imidazole-5-carboxamide was synthesized by the &#8216;one-pot&#8217; reductive cyclization of <i>N</i>-(4-methoxyphenyl)-3-nitro-4-(propylamino)benzamide with 3,4-dimethoxybenzaldehyde, using sodium dithionite as a reductive cyclizing agent using DMSO as a solvent. The structure of newly synthesized compound was elucidated based on IR, ¹H-NMR, ¹³C-NMR, and LC-MS data.