Fast determination of minoxidil by photometric flow titration
A photometric flow titration based on the redox reaction between KMnO 4 and minoxidil is described. The best titration results were observed at 3.20 x 10 -4 mol L -1 KMnO 4 and 1.00 x 10 -3 mol L -1 minoxidil, using the minoxidil solutions as titrant. The flow rate was fixed at 17 mL min -1 and the...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Universidade Estadual Paulista
2018-05-01
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| Series: | Eclética Química |
| Online Access: | https://revista.iq.unesp.br/ojs/index.php/ecletica/article/view/474 |
| Summary: | A photometric flow titration based on the redox reaction between KMnO 4 and minoxidil is
described. The best titration results were observed at 3.20 x 10 -4 mol L -1 KMnO 4 and 1.00 x 10 -3 mol L -1
minoxidil, using the minoxidil solutions as titrant. The flow rate was fixed at 17 mL min -1 and the titrant
was added to the system in aliquots of 500 μL, the color changes were monitored at 550 nm. The method
was applied to commercial samples and compared with the results from a chromatographic procedure.
Recoveries from 97.6 to 102.8 % were observed depending on the sample. Comparison with the
chromatographic procedure reveled relative errors of 3.5 - 4.0 %. |
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| ISSN: | 1678-4618 |