Failure of intravenous or intracardiac delivery of mesenchymal stromal cells to improve outcomes after focal traumatic brain injury in the female rat.

Mesenchymal stromal cells secrete a variety of anti-inflammatory factors and may provide a regenerative medicine option for the treatment of traumatic brain injury. The present study investigates the efficacy of multiple intravenous or intracardiac administrations of rat mesenchymal stromal cells or...

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Bibliographic Details
Main Authors: L Christine Turtzo, Matthew D Budde, Dana D Dean, Eric M Gold, Bobbi K Lewis, Lindsay Janes, Jacob Lescher, Tiziana Coppola, Angela Yarnell, Neil E Grunberg, Joseph A Frank
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4422703?pdf=render