Anticandidal Activity of Kalopanaxsaponin A: Effect on Proliferation, Cell Morphology, and Key Virulence Attributes of Candida albicans

Anticandidal Activity of Kalopanaxsaponin A: Effect on Proliferation, Cell Morphology, and Key Virulence Attributes of Candida albicans

BackgroundThe pathogenicity of Candida albicans is attributed to various virulence factors including adhesion to the surface of epithelial cells or mucosa, germ tube formation, hyphal morphogenesis, development of drug resistant biofilms, and so on. The objective of this study was to investigate the...

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Bibliographic Details
Main Authors: Ying Li, Mingzhu Shan, Mingju Yan, Huankai Yao, Yuechen Wang, Bing Gu, Zuobin Zhu, Hongchun Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Microbiology
Subjects:
Kalopanaxsaponin A
Candida albicans
virulence factors
hyphae
farnesol
cAMP
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.02844/full

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