Function of P2X4 Receptors Is Directly Modulated by a 1:1 Stoichiometric Interaction With 5-HT3A Receptors

Function of P2X4 Receptors Is Directly Modulated by a 1:1 Stoichiometric Interaction With 5-HT3A Receptors

Interacting receptors at the neuronal plasma membrane represent an additional regulatory mode for intracellular transduction pathways. P2X4 receptor triggers fast neurotransmission responses via a transient increase in intracellular Ca2+ levels. It has been proposed that the P2X4 receptor interacts...

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Bibliographic Details
Main Authors: Paola Soto, Pablo S. Gaete, Christian Fuentes, Benjamin Lozano, Pamela A. Naulin, Xavier F. Figueroa, Nelson Patricio Barrera
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Cellular Neuroscience
Subjects:
receptor-receptor interaction
atomic force microscopy
stoichiometry
P2X4 receptor
5-HT3A receptor
intracellular Ca2+
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2020.00106/full

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