Curcuminoids as EBV Lytic Activators for Adjuvant Treatment in EBV-Positive Carcinomas

Curcuminoids as EBV Lytic Activators for Adjuvant Treatment in EBV-Positive Carcinomas

Epstein-Barr virus (EBV) persists in nasopharyngeal (NPC) and gastric carcinomas (EBVaGC) in a tightly latent form. Cytolytic virus activation (CLVA) therapy employs gemcitabine and valproic acid (GCb+VPA) to reactivate latent EBV into the lytic phase and antiviral valganciclovir to enhance cell dea...

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Bibliographic Details
Main Authors: Octavia Ramayanti, Mitch Brinkkemper, Sandra A. W. M. Verkuijlen, Leni Ritmaleni, Mei Lin Go, Jaap M. Middeldorp
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:Cancers
Subjects:
Epstein-Barr virus
EBV
nasopharyngeal carcinoma
gastric cancer
curcumin
curcuminoids
virus-targeted therapy
cytolytic virus activation (CLVA)
oral adjuvant therapy
Online Access:http://www.mdpi.com/2072-6694/10/4/89

Internet

http://www.mdpi.com/2072-6694/10/4/89

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