Reversal of oncogene transformation and suppression of tumor growth by the novel IGF1R kinase inhibitor A-928605

Reversal of oncogene transformation and suppression of tumor growth by the novel IGF1R kinase inhibitor A-928605

<p>Abstract</p> <p>Background</p> <p>The insulin-like growth factor (IGF) axis is an important signaling pathway in the growth and survival of many cell and tissue types. This pathway has also been implicated in many aspects of cancer progression from tumorigenesis to m...

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Main Authors: Buchanan Fritz G, Donawho Cherrie, Sheppard George S, Johnson Eric F, Soni Niru B, Grudzien Meagan M, Zhang Qian, Hubbard Robert D, Wang Yi-Chun, Meulbroek Jonathan A, Jung Paul M, Pappano William N, Davidsen Steven K, Bell Randy L, Wang Jieyi
Format: Article
Language:English
Published: BMC 2009-09-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/9/314

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