Therapeutic response of immunoglobulin 4-related aortitis and pancreatitis demonstrated by diffusion-weighted MRI

Immunoglobulin (IgG) 4-related disease is a systemic inflammatory disease, and it affects vascular system as aortitis, periaortitis, or aneurysm. However, due to a lack of serum biomarker on aortic damage and the multiorgan involvement, it is difficult to assess aortic inflammatory activity of IgG4-...

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Main Authors:	Shogo Doi, Yasuyoshi Kuroiwa, PhD, Kazunori Kusumoto, MD, Atsushi Yamashita, MD, PhD, Eiji Furukoji, MD, PhD, Hiroshi Tai, MD, Yasushi Kihara, MD, Toshinori Hirai, MD, PhD, Yujiro Asada, MD, PhD, Takuroh Imamura, MD, PhD
Format:	Article
Language:	English
Published:	Elsevier 2019-09-01
Series:	Radiology Case Reports
Online Access:	http://www.sciencedirect.com/science/article/pii/S1930043319302365

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spelling	doaj-eb0cc8aec7524ff18ef013199aa30bde2020-11-24T21:54:56ZengElsevierRadiology Case Reports1930-04332019-09-0114911321135Therapeutic response of immunoglobulin 4-related aortitis and pancreatitis demonstrated by diffusion-weighted MRIShogo Doi0Yasuyoshi Kuroiwa, PhD1Kazunori Kusumoto, MD2Atsushi Yamashita, MD, PhD3Eiji Furukoji, MD, PhD4Hiroshi Tai, MD5Yasushi Kihara, MD6Toshinori Hirai, MD, PhD7Yujiro Asada, MD, PhD8Takuroh Imamura, MD, PhD9Department of Radiological Technology, Koga General Hospital, Miyazaki, JapanDepartment of Radiological Technology, Koga General Hospital, Miyazaki, Japan; Department of Pathology, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki 889-1692, JapanDepartment of Internal Medicine, Koga General Hospital, Miyazaki, JapanDepartment of Pathology, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki 889-1692, Japan; Corresponding author.Department of Radiology, Faculty of Medicine, University of Miyazaki, Miyazaki, JapanDepartment of Internal Medicine, Koga General Hospital, Miyazaki, JapanDepartment of Radiology, Koga General Hospital, Miyazaki, JapanDepartment of Radiology, Faculty of Medicine, University of Miyazaki, Miyazaki, JapanDepartment of Pathology, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki 889-1692, JapanDepartment of Internal Medicine, Koga General Hospital, Miyazaki, JapanImmunoglobulin (IgG) 4-related disease is a systemic inflammatory disease, and it affects vascular system as aortitis, periaortitis, or aneurysm. However, due to a lack of serum biomarker on aortic damage and the multiorgan involvement, it is difficult to assess aortic inflammatory activity of IgG4-related disease. We described a case of IgG4-related pancreatitis and aortitis, which was visualized with magnetic resonance merged image of diffusion weighted and T1 weighted images. The aortic signal intensity or apparent diffusion coefficient value reduced or increased after oral prednisone administration, respectively. Magnetic resonance diffusion weighted image and apparent diffusion coefficient may be a useful imaging tool for assessment of vascular inflammation in IgG4-related aortitis. Keywords: Immunoglobulin (IgG) 4-related disease, Aortitis, Magnetic resonance imaging, Diffusion weighted imaginghttp://www.sciencedirect.com/science/article/pii/S1930043319302365
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Shogo Doi Yasuyoshi Kuroiwa, PhD Kazunori Kusumoto, MD Atsushi Yamashita, MD, PhD Eiji Furukoji, MD, PhD Hiroshi Tai, MD Yasushi Kihara, MD Toshinori Hirai, MD, PhD Yujiro Asada, MD, PhD Takuroh Imamura, MD, PhD
spellingShingle	Shogo Doi Yasuyoshi Kuroiwa, PhD Kazunori Kusumoto, MD Atsushi Yamashita, MD, PhD Eiji Furukoji, MD, PhD Hiroshi Tai, MD Yasushi Kihara, MD Toshinori Hirai, MD, PhD Yujiro Asada, MD, PhD Takuroh Imamura, MD, PhD Therapeutic response of immunoglobulin 4-related aortitis and pancreatitis demonstrated by diffusion-weighted MRI Radiology Case Reports
author_facet	Shogo Doi Yasuyoshi Kuroiwa, PhD Kazunori Kusumoto, MD Atsushi Yamashita, MD, PhD Eiji Furukoji, MD, PhD Hiroshi Tai, MD Yasushi Kihara, MD Toshinori Hirai, MD, PhD Yujiro Asada, MD, PhD Takuroh Imamura, MD, PhD
author_sort	Shogo Doi
title	Therapeutic response of immunoglobulin 4-related aortitis and pancreatitis demonstrated by diffusion-weighted MRI
title_short	Therapeutic response of immunoglobulin 4-related aortitis and pancreatitis demonstrated by diffusion-weighted MRI
title_full	Therapeutic response of immunoglobulin 4-related aortitis and pancreatitis demonstrated by diffusion-weighted MRI
title_fullStr	Therapeutic response of immunoglobulin 4-related aortitis and pancreatitis demonstrated by diffusion-weighted MRI
title_full_unstemmed	Therapeutic response of immunoglobulin 4-related aortitis and pancreatitis demonstrated by diffusion-weighted MRI
title_sort	therapeutic response of immunoglobulin 4-related aortitis and pancreatitis demonstrated by diffusion-weighted mri
publisher	Elsevier
series	Radiology Case Reports
issn	1930-0433
publishDate	2019-09-01
description	Immunoglobulin (IgG) 4-related disease is a systemic inflammatory disease, and it affects vascular system as aortitis, periaortitis, or aneurysm. However, due to a lack of serum biomarker on aortic damage and the multiorgan involvement, it is difficult to assess aortic inflammatory activity of IgG4-related disease. We described a case of IgG4-related pancreatitis and aortitis, which was visualized with magnetic resonance merged image of diffusion weighted and T1 weighted images. The aortic signal intensity or apparent diffusion coefficient value reduced or increased after oral prednisone administration, respectively. Magnetic resonance diffusion weighted image and apparent diffusion coefficient may be a useful imaging tool for assessment of vascular inflammation in IgG4-related aortitis. Keywords: Immunoglobulin (IgG) 4-related disease, Aortitis, Magnetic resonance imaging, Diffusion weighted imaging
url	http://www.sciencedirect.com/science/article/pii/S1930043319302365
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Therapeutic response of immunoglobulin 4-related aortitis and pancreatitis demonstrated by diffusion-weighted MRI

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