Guanine Deaminase Stimulates Ultraviolet-induced Keratinocyte Senescence in Seborrhoeic Keratosis via Guanine Metabolites

Guanine Deaminase Stimulates Ultraviolet-induced Keratinocyte Senescence in Seborrhoeic Keratosis via Guanine Metabolites

DNA damage and oxidative stress play a critical role in photoageing. Seborrhoeic keratosis (SK) affects sunlight-exposed sites in aged individuals. This study examined the mechanism of photoageing in SK. The guanine deaminase gene, which is involved in purine metabolism, was upregulated with uric ac...

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Bibliographic Details
Main Authors:	Kyung Ah Cheong, Ai-Young Lee
Format:	Article
Language:	English
Published:	Society for Publication of Acta Dermato-Venereologica 2020-04-01
Series:	Acta Dermato-Venereologica
Subjects:	seborrhoeic keratosis guanine deaminase uv-induced keratinocyte senescence uric acid reactive oxygen species dna damage.
Online Access:	https://www.medicaljournals.se/acta/content/html/10.2340/00015555-3473

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