Tranexamic Acid Promotes Murine Bone Marrow-Derived Osteoblast Proliferation and Inhibits Osteoclast Formation In Vitro

Tranexamic Acid Promotes Murine Bone Marrow-Derived Osteoblast Proliferation and Inhibits Osteoclast Formation In Vitro

Despite modern surgical trauma care, bleeding contributes to one-third of trauma-related death. A significant improvement was obtained through the introduction of tranexamic acid (TXA), which today is widely used in emergency and elective orthopedic surgery to control bleeding. However, concerns rem...

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Bibliographic Details
Main Authors: Anke Baranowsky, Jessika Appelt, Kristina Tseneva, Shan Jiang, Denise Jahn, Serafeim Tsitsilonis, Karl-Heinz Frosch, Johannes Keller
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
tranexamic acid
osteoblast
osteoclast
macrophages
bone regeneration
Online Access:https://www.mdpi.com/1422-0067/22/1/449

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