The Role of High-Mobility Group Box-1 and Its Crosstalk with Microbiome in Rheumatoid Arthritis

The Role of High-Mobility Group Box-1 and Its Crosstalk with Microbiome in Rheumatoid Arthritis

Rheumatoid arthritis (RA) is a chronic, definitely disabling, and potentially severe autoimmune disease. Although an increasing number of patients are affected, a key treatment for all patients has not been discovered. High-mobility group box-1 (HMGB1) is a nuclear protein passively and actively rel...

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Bibliographic Details
Main Authors:	Federico Biscetti, Andrea Flex, Stefano Alivernini, Barbara Tolusso, Elisa Gremese, Gianfranco Ferraccioli
Format:	Article
Language:	English
Published:	Hindawi Limited 2017-01-01
Series:	Mediators of Inflammation
Online Access:	http://dx.doi.org/10.1155/2017/5230374

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