Retargeting of Viruses to Generate Oncolytic Agents

Oncolytic virus therapy is based on the ability of viruses to effectively infect and kill tumor cells without destroying the normal tissues. While some viruses seem to have a natural preference for tumor cells, most viruses require the modification of their tropism to specifically enter and replicat...

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Bibliographic Details
Main Authors: M. H. Verheije, P. J. M. Rottier
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Advances in Virology
Online Access:http://dx.doi.org/10.1155/2012/798526