Docking-based modeling of protein-protein interfaces for extensive structural and functional characterization of missense mutations.

Next-generation sequencing (NGS) technologies are providing genomic information for an increasing number of healthy individuals and patient populations. In the context of the large amount of generated genomic data that is being generated, understanding the effect of disease-related mutations at mole...

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Bibliographic Details
Main Authors: Didier Barradas-Bautista, Juan Fernández-Recio
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5571915?pdf=render