Novel brain arteriovenous malformation mouse models for type 1 hereditary hemorrhagic telangiectasia.

Endoglin (ENG) is a causative gene of type 1 hereditary hemorrhagic telangiectasia (HHT1). HHT1 patients have a higher prevalence of brain arteriovenous malformation (AVM) than the general population and patients with other HHT subtypes. The pathogenesis of brain AVM in HHT1 patients is currently un...

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Bibliographic Details
Main Authors: Eun-Jung Choi, Wanqiu Chen, Kristine Jun, Helen M Arthur, William L Young, Hua Su
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3919779?pdf=render