Signal propagation in proteins and relation to equilibrium fluctuations.

Elastic network (EN) models have been widely used in recent years for describing protein dynamics, based on the premise that the motions naturally accessible to native structures are relevant to biological function. We posit that equilibrium motions also determine communication mechanisms inherent t...

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Bibliographic Details
Main Authors: Chakra Chennubhotla, Ivet Bahar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-09-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC1988854?pdf=render