Modeling the Influence of Chronic Sleep Restriction on Cortisol Circadian Rhythms, with Implications for Metabolic Disorders

Modeling the Influence of Chronic Sleep Restriction on Cortisol Circadian Rhythms, with Implications for Metabolic Disorders

Chronic sleep deficiency is prevalent in modern society and is associated with increased risk of metabolic and other diseases. While the mechanisms by which chronic sleep deficiency induces pathophysiological changes are yet to be elucidated, the hypothalamic–pituitary–adrenal (HPA) axis may be an i...

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Bibliographic Details
Main Authors: Rohit Rao, Pramod Somvanshi, Elizabeth B. Klerman, Charles Marmar, Francis J. Doyle
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Metabolites
Subjects:
mathematical modeling
HPA axis
cortisol
sleep/wake cycle
sleep restriction
circadian rhythms
Online Access:https://www.mdpi.com/2218-1989/11/8/483

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https://www.mdpi.com/2218-1989/11/8/483

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