Postconditioning inhibits myocardial apoptosis during prolonged reperfusion via a JAK2-STAT3-Bcl-2 pathway

Postconditioning inhibits myocardial apoptosis during prolonged reperfusion via a JAK2-STAT3-Bcl-2 pathway

<p>Abstract</p> <p>Background</p> <p>Postconditioning (PostC) inhibits myocardial apoptosis after ischemia-reperfusion (I/R) injury. The JAK2-STAT3 pathway has anti-apoptotic effects and plays an essential role in the late protection of preconditioning. Our aim was to i...

Full description

Bibliographic Details
Main Authors: Liang Degang, Modi Paul, Xia Dachuan, Zhang Wenjuan, Tian Yikui, Wei Minxin
Format: Article
Language:English
Published: BMC 2011-08-01
Series:Journal of Biomedical Science
Subjects:
Ischemia/reperfusion injury
apoptosis
postconditioning
JAK2-STAT3 pathway
Bcl-2
Online Access:http://www.jbiomedsci.com/content/18/1/53

Similar Items

Similar Items