In vitro modulation of Bcl-2 levels in small cell lung cancer cells: effects on cell viability

In vitro modulation of Bcl-2 levels in small cell lung cancer cells: effects on cell viability

Small cell lung cancer (SCLC) is an aggressive disease, representing 15% of all cases of lung cancer, has high metastatic potential and low prognosis that urgently demands the development of novel therapeutic approaches. One of the proposed approaches has been the down-regulation of BCL2, with poorl...

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Bibliographic Details
Main Authors:	A.O. Santos, J.P. Pereira, M.C. Pedroso de Lima, S. Simões, J.N. Moreira
Format:	Article
Language:	English
Published:	Associação Brasileira de Divulgação Científica 2010-10-01
Series:	Brazilian Journal of Medical and Biological Research
Subjects:	Small cell lung cancer Gene silencing Bcl-2 siRNA Antisense ODN Flow cytometry Chemosensitization
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010001000013

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