DiffSLC: A graph centrality method to detect essential proteins of a protein-protein interaction network.

Identification of central genes and proteins in biomolecular networks provides credible candidates for pathway analysis, functional analysis, and essentiality prediction. The DiffSLC centrality measure predicts central and essential genes and proteins using a protein-protein interaction network. Net...

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Bibliographic Details
Main Authors: Divya Mistry, Roger P Wise, Julie A Dickerson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5679606?pdf=render