Effects of voluntary and forced exercise on plaque deposition, hippocampal volume, and behavior in the Tg2576 mouse model of Alzheimer's disease

Effects of voluntary and forced exercise on plaque deposition, hippocampal volume, and behavior in the Tg2576 mouse model of Alzheimer's disease

We examined the effects of voluntary (16 weeks of wheel running) and forced (16 weeks of treadmill running) exercise on memory-related behavior, hippocampal volume, thioflavine-stained plaque number, and soluble Aβ levels in brain tissue in the Tg2576 mouse model of Alzheimer's disease (AD). Vo...

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Bibliographic Details
Main Authors:	Carla M. Yuede, Scott D. Zimmerman, Hongxin Dong, Matthew J. Kling, Adam W. Bero, David M. Holtzman, Benjamin F. Timson, John G. Csernansky
Format:	Article
Language:	English
Published:	Elsevier 2009-09-01
Series:	Neurobiology of Disease
Subjects:	Alzheimer's disease Voluntary exercise Forced exercise Tg2576 Object recognition Hippocampal volume
Online Access:	http://www.sciencedirect.com/science/article/pii/S0969996109001405

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